Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759101 | 0.80 | MAPK1 (0.49) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28425880 | 0.79 | MAPT (0.41) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16102502 | 0.76 | MEN1 (0.46) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL21988801 | 0.73 | MEN1 (0.44) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL28294729 | 0.73 | MAPT (0.37) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL24214955 | 0.73 | MAPT (0.46) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL30949517 | 0.73 | KDM4E (0.46) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL671956 | 0.73 | ALDH1A1 (0.46) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL16371832 | 0.73 | KDM4E (0.46) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL21988641 | 0.71 | MEN1 (0.44) | KMT2AMAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694351-B | Benzazepine derivatives, process for their preparation and their use in medicine | 江苏恒瑞医药股份有限公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-109694351-A | Benzo-aza * derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-04-30 | — | — | CN | disclosed |