Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759101 | 0.80 | MAPK1 (0.49) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28293040 | 0.73 | KMT2A (0.40) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL29001798 | 0.73 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL161297 | 0.73 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL4878068 | 0.73 | NOTUM (0.44) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7237526 | 0.71 | KDM4E (0.40) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL21988636 | 0.71 | KDM4E (0.40) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28425880 | 0.70 | MAPT (0.41) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL27945389 | 0.70 | ALDH1A1 (0.42) | MAPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL27934781 | 0.70 | TDO2 (0.44) | MAPTKMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694351-A | Benzo-aza * derivative, preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2019-04-30 | — | — | CN | disclosed |