Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28293040 | 0.79 | KMT2A (0.40) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8759101 | 0.76 | MAPK1 (0.49) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL28294729 | 0.70 | MAPT (0.37) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL540011 | 0.68 | NOTUM (0.58) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL4010773 | 0.68 | ENPP2 (0.52) | ALDH1A1LMNAGAAENPP2 | |
| SCHEMBL27639051 | 0.68 | ACLY (0.51) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL25806679 | 0.68 | TP53 (0.44) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL552775 | 0.67 | LMNA (0.47) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL15266274 | 0.67 | MAPK1 (0.49) | MAPTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL8705696 | 0.67 | SLC9A1 (0.43) | MAPTMEN1ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694351-B | Benzazepine derivatives, process for their preparation and their use in medicine | 江苏恒瑞医药股份有限公司 | 2020-07-28 | — | — | CN | disclosed |