SCHEMBL28293341

SCHEMBL28293341

COc1ccc(N(C(N)=O)S(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.51
ALDH1A1 P00352 8/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
MAPT P10636 6/20 0.46
GAA P10253 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
LMNA P02545 4/20 0.46
HSP90AA1 P07900 1/20 0.45
KMT2A Q03164 7/20 0.44
F2 P00734 1/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295296 0.86 NPC1 (0.48) TP53ALDH1A1MAPTGAACYP1A2
SCHEMBL20981709 0.86 HCRTR2 (0.43) KMT2AHPGDTSHR
SCHEMBL18546049 0.84 ALDH1A1 (0.63) TP53ALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL6331211 0.83 KCNA5 (0.43) TP53ALDH1A1SMN1; SMN2MAPTCYP3A4
SCHEMBL28293334 0.83 TP53 (0.47) TP53ALDH1A1MAPTLMNAKMT2A
SCHEMBL29150815 0.83 TP53 (0.48) TP53ALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL6244922 0.82 HCRTR2 (0.44) ALDH1A1MAPTLMNAKMT2AHTT
SCHEMBL28293338 0.78 PTGER1 (0.43) ALDH1A1SMN1; SMN2MAPTKMT2AHPGD
SCHEMBL9478142 0.78 TP53 (0.73) TP53ALDH1A1MAPTGAACYP1A2
SCHEMBL29430026 0.78 STS (0.49) ALDH1A1SMN1; SMN2MAPTGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790108-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2019-05-21 CN disclosed