SCHEMBL28295296

SCHEMBL28295296

CCOc1ccc(N(C(N)=O)S(=O)(=O)c2ccccc2C)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
HCRTR2 O43614 1/20 0.46
PARP10 Q53GL7 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
MAPT P10636 4/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
OXTR P30559 1/20 0.40
AVPR1A P37288 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293341 0.86 TP53 (0.51) ALDH1A1TSHRMAPTCYP1A2CYP3A4
SCHEMBL20981709 0.82 HCRTR2 (0.43) HCRTR2TSHRL3MBTL1KMT2A
SCHEMBL6244922 0.82 HCRTR2 (0.44) HCRTR2ALDH1A1MAPTL3MBTL1LMNA
SCHEMBL6331211 0.80 KCNA5 (0.43) HCRTR2ALDH1A1TSHRMAPTCYP3A4
SCHEMBL28293334 0.80 TP53 (0.47) HCRTR2ALDH1A1MAPTLMNATP53
SCHEMBL29430026 0.79 STS (0.49) NPC1RAB9AALDH1A1TSHRMAPT
SCHEMBL16670284 0.78 ACACB (0.46) NPC1RAB9AHCRTR2TSHRMAPT
SCHEMBL7601389 0.76 LMNA (0.44) NPC1RAB9AHCRTR2ALDH1A1MAPT
SCHEMBL9179644 0.73 NPC1 (0.43) NPC1RAB9AALDH1A1MAPTLMNA
SCHEMBL6326502 0.72 PARP1 (0.43) HCRTR2PARP10ALDH1A1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790108-A Thermal recording medium 奥古斯特科勒纸厂欧洲公司 2019-05-21 CN disclosed