Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20981709 | 0.88 | HCRTR2 (0.43) | HCRTR2HSD11B1KMT2AKCNJ6KCNJ5 | |
| SCHEMBL6331211 | 0.86 | KCNA5 (0.43) | TP53MAPTHCRTR2HSD11B1KMT2A | |
| SCHEMBL28293337 | 0.85 | LMNA (0.42) | TP53LMNAKDM4EMAPTHCRTR2 | |
| SCHEMBL6244922 | 0.84 | HCRTR2 (0.44) | LMNAMAPTHCRTR2HSD11B1KMT2A | |
| SCHEMBL28293341 | 0.83 | TP53 (0.51) | TP53LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL29150792 | 0.82 | LMNA (0.46) | TP53LMNAKDM4EMAPTHCRTR2 | |
| SCHEMBL28295296 | 0.80 | NPC1 (0.48) | TP53LMNAMAPTHCRTR2KMT2A | |
| SCHEMBL28295134 | 0.80 | RORC (0.39) | LMNAKDM4EHCRTR2HSD11B1KMT2A | |
| SCHEMBL6326502 | 0.77 | PARP1 (0.43) | TP53MAPTHCRTR2HSD11B1KMT2A | |
| SCHEMBL7999295 | 0.77 | LMNA (0.76) | TP53LMNAKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790108-A | Thermal recording medium | 奥古斯特科勒纸厂欧洲公司 | 2019-05-21 | — | — | CN | disclosed |