Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE1A | P54750 | 3/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10233676 | 0.74 | GRM5 (0.38) | GRM5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2437697 | 0.70 | HTR6 (0.43) | HTR2CHTR2BHTR6PDE5APDE4A | |
| SCHEMBL9485705 | 0.69 | NPC1 (0.49) | HTR2CHTR2BHTR6SMN1; SMN2NPC1 | |
| SCHEMBL19922957 | 0.69 | CDK1 (0.48) | PDE5APDE4APDE1APDE1BPDE4B | |
| SCHEMBL30450665 | 0.69 | CDK1 (0.48) | PDE5APDE4APDE1APDE1BPDE4B | |
| SCHEMBL10442246 | 0.69 | HTR2C (0.50) | HTR2CHTR2BHTR6SMN1; SMN2NPC1 | |
| SCHEMBL31068637 | 0.68 | CYP1A2 (0.66) | ALDH1A1HPGDHSD17B10LMNAMEN1 | |
| SCHEMBL30298001 | 0.68 | HTR6 (0.50) | HTR2CHTR2BHTR6SMN1; SMN2NPC1 | |
| SCHEMBL19922741 | 0.67 | CTSS (0.44) | PDE5APDE4APDE1APDE1BPDE4B | |
| SCHEMBL30450440 | 0.67 | CTSS (0.44) | PDE5APDE4APDE1APDE1BPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790167-A | SGC stimulators | 艾恩伍德医药品股份有限公司 | 2019-05-21 | — | — | CN | disclosed |