Iodobenzene

Iodobenzene

SCHEMBL28293584

Ic1ccccc1.[N-]=[N+]=NS(=O)(=O)N=[N+]=[N-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.32
HTR6 P50406 1/20 0.31
APP P05067 1/20 0.31
PTPN1 P18031 1/20 0.30
PTPN6 P29350 1/20 0.30
PTPN11 Q06124 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA5A P35218 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL413377 0.83 ALDH1A1 (0.41) PTGS2HTR6CA1CA2CA9
Benzene SCHEMBL8170940 0.82
Fluorobenzene SCHEMBL27951760 0.81 KMT2A (0.38) PTGS2
Naphthalene SCHEMBL8355966 0.80 CYP2A6 (0.38) CA1CA2CA5ACA9
Phenol SCHEMBL9645845 0.79 TDP1 (0.46) CA1CA2CA9
Toluene SCHEMBL2923984 0.79 LMNA (0.46) CA1CA2CA9
SCHEMBL10584897 0.79 SRC (0.31) HTR6CA1CA2CA5ACA9
Chlorobenzene SCHEMBL8552009 0.79 TSHR (0.46)
Diphenylether SCHEMBL16004650 0.78 LTA4H (0.48) CA1CA2CA9
SCHEMBL27738800 0.77 LMNA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109761875-A A kind of new method constructing amido bond 盐城工学院 2019-05-17 CN claimed
CN-109761875-A A kind of new method constructing amido bond 盐城工学院 2019-05-17 CN disclosed