Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP7 | P09237 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL8170940 | 0.85 | — | — | |
| Fluorobenzene SCHEMBL27951760 | 0.84 | KMT2A (0.38) | PTGS2GAA | |
| Naphthalene SCHEMBL8355966 | 0.84 | CYP2A6 (0.38) | ALDH1A1CA1CA2CA9 | |
| SCHEMBL10584897 | 0.83 | SRC (0.31) | CA1CA2CA9HTR6 | |
| Chlorobenzene SCHEMBL8552009 | 0.83 | TSHR (0.46) | ALDH1A1 | |
| Iodobenzene SCHEMBL28293584 | 0.83 | PTGS2 (0.32) | CA1CA2CA9PTGS2HTR6 | |
| Phenol SCHEMBL9645845 | 0.83 | TDP1 (0.46) | CA1CA2CA9CA12GAA | |
| Toluene SCHEMBL2923984 | 0.83 | LMNA (0.46) | ALDH1A1CA1CA2CA9CA12 | |
| Diphenylether SCHEMBL16004650 | 0.81 | LTA4H (0.48) | CA1CA2CA9 | |
| Anthraquinone SCHEMBL23780306 | 0.80 | MEN1 (0.52) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171014-A | Method for obtaining a foamed laminar product | ANTOLIN GRUPO ING SA | 2011-08-31 | — | — | CN | claimed |
| EP-2393552-B1 | A CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-9708292-B2 | Cyanopyrimidine derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| CN-102307621-B | Cyanopyrimidine Derivatives | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-01 | — | — | CN | disclosed |
| CN-102171015-B | Method for manufacturing a motor vehicle trimming | ANTOLIN GRUPO ING SA | 2014-07-30 | — | — | CN | disclosed |
| CN-101959951-B | Rubber composition containing ricinoleic acid polymer rubber and use thereof | MITSUI CHEMICALS INC | 2012-11-14 | — | — | CN | disclosed |
| US-20120022077-A1 | NOVEL CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
| CN-102307621-A | Novel cyanopyrimidine derivative | OTSUKA PHARMA CO LTD | 2012-01-04 | — | — | CN | disclosed |
| EP-2393552-A1 | A NOVEL CYANOPYRIMIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| CN-102171014-A | Method for obtaining a foamed laminar product | ANTOLIN GRUPO ING SA | 2011-08-31 | — | — | CN | disclosed |
| CN-102171015-A | Method for manufacturing a motor vehicle trimming | ANTOLIN GRUPO ING SA (ES) | 2011-08-31 | — | — | CN | disclosed |
| CN-101959951-A | Rubber composition containing ricinoleic acid polymer rubber and use thereof | MITSUI CHEMICALS INC | 2011-01-26 | — | — | CN | disclosed |
| WO-2010090299-A1 | A NOVEL CYANOPYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-12 | — | — | WO | disclosed |
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| CN-1395575-A | Novel piperidine compounds and drugs containing the same | EISAI CO LTD (JP) | 2003-02-05 | — | — | CN | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |
| US-4009294-A | Process of preparing fire-retardant natural and synthetic fibers | HERCULES INCORPORATED (US) | 1977-02-22 | — | — | US | disclosed |
| US-3957835-A | BROMINATED AZIDO FIRE RETARDANTS | HERCULES INCORPORATED (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022077-A1 | NOVEL CYANOPYRIMIDINE DERIVATIVE | ADORA2A, ADORA1, ADORA3 | ALDH1A1 1232/4885CA1 4160/4885CA2 2715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.