Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PAM | P19021 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295477 | 1.00 | KCNH2 (0.33) | KCNH2PAMALOX5PTGS1PTGS2 | |
| SCHEMBL9131838 | 0.76 | ALOX5 (0.50) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9131824 | 0.76 | ALOX5 (0.50) | ALOX5PTGS1PTGS2 | |
| SCHEMBL28835558 | 0.75 | RELA (0.34) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL14174574 | 0.73 | ALDH1A1 (0.58) | — | |
| SCHEMBL8442224 | 0.73 | NFE2L2 (0.50) | ALOX5PTGS1PTGS2CA1 | |
| SCHEMBL5704309 | 0.73 | NFE2L2 (0.50) | ALOX5PTGS1PTGS2CA1 | |
| SCHEMBL27985142 | 0.72 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL15623096 | 0.72 | APP (0.59) | KCNH2 | |
| SCHEMBL18905532 | 0.71 | HTR2A (0.36) | KCNH2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651209-A | A kind of method that carbon-to-carbon σ-bond activation prepares (E) -1- phenyl -4- sulfonyl but-1-ene class compound | 湖南理工学院 | 2019-04-19 | — | — | CN | claimed |
| CN-109651209-B | Method for preparing (E) -1-phenyl-4-sulfonyl butyl-1-alkene compound by activating carbon-carbon sigma-bond | 湖南理工学院 | 2020-08-11 | — | — | CN | disclosed |
| CN-109651209-B | Method for preparing (E) -1-phenyl-4-sulfonyl butyl-1-alkene compound by activating carbon-carbon sigma-bond | 湖南理工学院 | 2020-08-11 | — | — | CN | disclosed |
| CN-109651210-B | Preparation method of 3-sulfonyl-1, 2-dihydronaphthalene compound | 湖南理工学院 | 2020-08-07 | — | — | CN | disclosed |
| CN-109651209-A | A kind of method that carbon-to-carbon σ-bond activation prepares (E) -1- phenyl -4- sulfonyl but-1-ene class compound | 湖南理工学院 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651209-A | A kind of method that carbon-to-carbon σ-bond activation prepares (E) -1- phenyl -4- sulfonyl but-1-ene class compound | 湖南理工学院 | 2019-04-19 | — | — | CN | disclosed |
| CN-109651209-A | A kind of method that carbon-to-carbon σ-bond activation prepares (E) -1- phenyl -4- sulfonyl but-1-ene class compound | 湖南理工学院 | 2019-04-19 | — | — | CN | disclosed |