Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.52 |
| ▸ | PTPRC | P08575 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | PTPRF | P10586 | 2/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559293 | 0.87 | BACE1 (0.45) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL1243588 | 0.83 | BACE1 (0.52) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL30172862 | 0.83 | BACE1 (0.52) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL10343653 | 0.72 | TTR (0.43) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL30895284 | 0.71 | MAOA (0.50) | ALDH1A1PTPRCKMT2AMEN1LMNA | |
| SCHEMBL503745 | 0.71 | MAOA (0.50) | ALDH1A1PTPRCKMT2AMEN1LMNA | |
| SCHEMBL342409 | 0.71 | KDM4E (1.00) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| Anthraquinone SCHEMBL183074 | 0.71 | MEN1 (0.86) | MAPTKDM4EALDH1A1CYP3A4HPGD | |
| SCHEMBL7354968 | 0.71 | MAOA (0.50) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL366178 | 0.71 | PTPN1 (0.63) | MAPTKDM4EALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734642-B | Synthesis and application of naphthalenone-sulfoxide ylide hybrid | 河南师范大学 | 2020-10-09 | — | — | CN | disclosed |
| CN-109734642-A | Naphthalenone-sulfoxide ylide hybrid synthesis and application | 河南师范大学 | 2019-05-10 | — | — | CN | disclosed |