Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22922689 | 0.79 | GPR84 (0.53) | LMNAHTTKMT2AMAPK1MAPT | |
| SCHEMBL29871975 | 0.79 | GPR84 (0.53) | LMNAHTTKMT2AMAPK1MAPT | |
| SCHEMBL6985439 | 0.77 | MAPK1 (0.48) | LMNAHTTKMT2AKDM4EMAPK1 | |
| SCHEMBL9456621 | 0.77 | GPR84 (0.54) | LMNAHTTKMT2AKDM4EMAPK1 | |
| SCHEMBL5261760 | 0.74 | GPR84 (0.46) | LMNAHTTKMT2AKDM4EMAPK1 | |
| SCHEMBL27663359 | 0.73 | LMNA (0.48) | LMNAHTTKMT2AMAPK1MAPT | |
| SCHEMBL11577771 | 0.73 | LMNA (0.44) | LMNAHTTKMT2AKDM4EMAPK1 | |
| SCHEMBL6614577 | 0.73 | SLC6A4 (0.51) | — | |
| SCHEMBL5260086 | 0.72 | GPR84 (0.47) | LMNAHTTKMT2AKDM4EMAPK1 | |
| SCHEMBL2074732 | 0.71 | CYP2D6 (0.57) | LMNAHTTKMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109645008-A | The application of donaxine and its derivative in Antiphytoviral and germ | 河北工业大学 | 2019-04-19 | — | — | CN | claimed |
| CN-109645008-A | The application of donaxine and its derivative in Antiphytoviral and germ | 河北工业大学 | 2019-04-19 | — | — | CN | disclosed |