SCHEMBL28293855

SCHEMBL28293855

C1=CCN(C(c2ccccc2)c2c[nH]c3ccccc23)C=C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 2/20 0.45
MAPT P10636 5/20 0.44
GPR84 Q9NQS5 3/20 0.43
FFAR1 O14842 2/20 0.43
CYP2D6 P10635 2/20 0.41
NR3C1 P04150 1/20 0.41
PGR P06401 1/20 0.41
NR3C2 P08235 1/20 0.41
AR P10275 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
KCNH2 Q12809 1/20 0.41
NOD2 Q9HC29 1/20 0.41
MGAM O43451 2/20 0.40
GAA P10253 2/20 0.40
SI P14410 2/20 0.40
MGAM2 Q2M2H8 2/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293850 0.87 NR3C1 (0.55) SRCMAPTGPR84FFAR1NR3C1
SCHEMBL28293853 0.82 MAPT (0.43) SRCMAPTGPR84FFAR1NR3C1
SCHEMBL4469191 0.78 CRHBP (0.46) MAPTCYP2D6KCNH2MEN1KMT2A
Bromide SCHEMBL30297450 0.76 CRHBP (0.44) MAPTCYP2D6KCNH2MEN1KMT2A
SCHEMBL5260086 0.73 GPR84 (0.47) SRCMAPTGPR84FFAR1CYP2D6
SCHEMBL5261760 0.72 GPR84 (0.46) SRCMAPTGPR84FFAR1CYP2D6
SCHEMBL3343111 0.68 MAPT (0.69) SRCMAPTGPR84FFAR1CYP2D6
SCHEMBL30040360 0.68 MAPT (0.69) SRCMAPTGPR84FFAR1CYP2D6
SCHEMBL10717194 0.68 NR3C1 (0.73) SRCMAPTGPR84FFAR1CYP2D6
SCHEMBL27981638 0.67 GPR84 (0.77) SRCMAPTGPR84FFAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109645008-A The application of donaxine and its derivative in Antiphytoviral and germ 河北工业大学 2019-04-19 CN disclosed