Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 known ✓ | Q07820 | 3/20 | 0.47 |
| ▸ | BCL2L1 known ✓ | Q07817 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.47 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9303438 | 0.94 | PPARA (0.52) | PPARASOAT1BIDMCL1BCL2L1 | |
| Sulfuric Acid SCHEMBL28318943 | 0.92 | PPARA (0.51) | PPARASOAT1BIDMCL1BCL2L1 | |
| Sulfuric Acid SCHEMBL9081730 | 0.90 | PPARA (0.49) | PPARASOAT1BIDMCL1BCL2L1 | |
| SCHEMBL28295855 | 0.89 | PPARA (0.49) | PPARASOAT1 | |
| Bicarbonate SCHEMBL1835637 | 0.89 | PPARA (0.59) | PPARASOAT1BIDMCL1BCL2L1 | |
| Methyl Alcohol SCHEMBL28181735 | 0.89 | PPARA (0.54) | PPARASOAT1BIDMCL1BCL2L1 | |
| SCHEMBL1026184 | 0.88 | PPARA (0.53) | PPARASOAT1BIDMCL1BCL2L1 | |
| Bicarbonate SCHEMBL1835039 | 0.87 | PPARA (0.57) | PPARASOAT1BIDMCL1BCL2L1 | |
| Bicarbonate SCHEMBL1838555 | 0.87 | PPARA (0.57) | PPARASOAT1BIDMCL1BCL2L1 | |
| Bicarbonate SCHEMBL27543186 | 0.87 | PPARA (0.57) | PPARASOAT1BIDMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661399-A | Cross-coupling methods | 芝诺罗耶尔蒂里程碑有限责任公司 | 2019-04-19 | — | — | CN | disclosed |