Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | METAP1 | P53582 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17625960 | 0.73 | — | — | |
| SCHEMBL17666270 | 0.70 | SYK (0.37) | F2RL1HCRTR1HCRTR2METAP2METAP1 | |
| SCHEMBL27928104 | 0.69 | SCN9A (0.41) | F2RL1HCRTR1HCRTR2METAP2METAP1 | |
| SCHEMBL16982960 | 0.68 | SYK (0.38) | F2RL1HCRTR1HCRTR2METAP2METAP1 | |
| SCHEMBL1868592 | 0.67 | SCN9A (0.40) | F2RL1HCRTR1HCRTR2METAP2METAP1 | |
| SCHEMBL14754342 | 0.66 | CASP6 (0.48) | F2RL1METAP2METAP1CASP6TSHR | |
| SCHEMBL26259959 | 0.65 | METAP2 (0.44) | F2RL1METAP2METAP1ALDH1A1TSHR | |
| SCHEMBL17661891 | 0.65 | F2RL1 (0.36) | F2RL1HCRTR1HCRTR2METAP2METAP1 | |
| SCHEMBL10151023 | 0.65 | MPL (0.50) | HCRTR1HCRTR2METAP2METAP1CASP6 | |
| SCHEMBL4082911 | 0.64 | MAPK1 (0.41) | HCRTR1HCRTR2CASP6MAPK1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |