Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111729 | 0.83 | NCF1 (0.72) | NCF1PNMTKDM4EALDH1A1PLA2G1B | |
| SCHEMBL16814882 | 0.83 | NCF1 (0.77) | NCF1PNMTDPP4KDM4EALDH1A1 | |
| SCHEMBL110730 | 0.81 | NCF1 (0.70) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL16814951 | 0.81 | NCF1 (0.70) | NCF1KDM4EALDH1A1PLA2G1BRAB9A | |
| SCHEMBL11503777 | 0.79 | MGLL (0.52) | NCF1HTR1AHTR2A | |
| SCHEMBL16814883 | 0.78 | NCF1 (0.49) | NCF1PNMTDPP4MC4RBRD4 | |
| SCHEMBL111193 | 0.78 | NCF1 (0.57) | NCF1ALDH1A1RAB9ABRD4 | |
| SCHEMBL29505669 | 0.78 | NCF1 (0.87) | NCF1KDM4EHTR1ABRD4HTR2A | |
| SCHEMBL16814952 | 0.78 | NCF1 (0.57) | NCF1PNMTKDM4EALDH1A1PLA2G1B | |
| SCHEMBL110927 | 0.78 | NCF1 (0.87) | NCF1KDM4EHTR1ABRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678806-A | A kind of monomethylation synthetic method of efficient aromatic primary amine | 淮安国瑞化工有限公司 | 2019-04-26 | — | — | CN | disclosed |