Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.69 |
| ▸ | QPCT | Q16769 | 9/20 | 0.58 |
| ▸ | QPCTL | Q9NXS2 | 8/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096521 | 0.88 | MMP12 (0.55) | MMP12QPCTQPCTLMAP4K4USP2 | |
| SCHEMBL2093317 | 0.86 | MMP12 (0.75) | MMP12QPCTQPCTLALDH1A1 | |
| SCHEMBL225932 | 0.82 | MMP12 (1.00) | MMP12QPCTQPCTLPOLBMAPT | |
| SCHEMBL29424791 | 0.82 | MMP12 (1.00) | MMP12QPCTQPCTLPOLBMAPT | |
| SCHEMBL8634290 | 0.80 | QPCT (0.68) | MMP12QPCTQPCTLMAPTALDH1A1 | |
| SCHEMBL13680531 | 0.80 | QPCT (0.60) | MMP12QPCTQPCTLMAP4K4MAPT | |
| SCHEMBL22418756 | 0.79 | QPCT (0.64) | QPCTQPCTLMAPTALDH1A1 | |
| SCHEMBL2462345 | 0.79 | QPCT (0.68) | QPCTQPCTLMAPTALDH1A1 | |
| Benzimidazole SCHEMBL15413095 | 0.78 | MMP12 (0.84) | MMP12QPCTQPCTLPOLBALDH1A1 | |
| SCHEMBL23227938 | 0.76 | QPCT (0.60) | QPCTQPCTLMAP4K4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107312008-B | A kind of catalysis prepares the catalyst and system and method for benzimidazole simultaneously [2,1-b] quinoline -6- ketone derivatives | 马鞍山市泰博化工科技有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-106866543-B | A method of benzimidazole compound is catalyzed and synthesized under microwave radiation in water phase | 福建医科大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-107312008-A | A kind of easy catalysis prepares the catalyst and system and method for benzimidazole simultaneously ketone derivatives of [2,1 b] quinoline 6 | 马鞍山市泰博化工科技有限公司 | 2017-11-03 | — | — | CN | disclosed |