Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901790 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL29010607 | 0.82 | NQO1 (0.62) | KMT2ANPSR1LMNAALDH1A1SMN1; SMN2 | |
| Nitric Acid SCHEMBL14696528 | 0.75 | RAB9A (0.49) | KMT2ALMNAALDH1A1SMN1; SMN2RAB9A | |
| Ethoxycarbonyl Group SCHEMBL27750267 | 0.74 | KMT2A (0.53) | KMT2ANPSR1LMNAALDH1A1SMN1; SMN2 | |
| Nitric Acid SCHEMBL20985027 | 0.74 | ALDH1A1 (0.54) | KMT2ANPSR1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14990810 | 0.72 | CYP3A4 (0.71) | KMT2ANPSR1LMNAALDH1A1SMN1; SMN2 | |
| Etocarlide SCHEMBL2593645 | 0.71 | MAPT (0.78) | KMT2ANPSR1LMNAALDH1A1SMN1; SMN2 | |
| Nitric Acid SCHEMBL14695936 | 0.71 | ACHE (0.44) | KMT2ALMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL45896 | 0.71 | PTGS2 (0.80) | KMT2ANPSR1LMNAALDH1A1MAPT | |
| Nitric Acid SCHEMBL5479789 | 0.70 | ALDH1A1 (0.54) | KMT2ALMNAALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109745833-A | A kind of hydroxyl proton type ionic liquid absorbent efficiently separating recycling ammonia | 中国科学院过程工程研究所 | 2019-05-14 | — | — | CN | disclosed |