Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292577 | 0.88 | CCNC (0.48) | CNR2L3MBTL1CCNCCDK8CDK19 | |
| SCHEMBL28940894 | 0.82 | CCNC (0.39) | CNR2L3MBTL1CCNCCDK8CDK19 | |
| SCHEMBL28292566 | 0.81 | MAOB (0.49) | L3MBTL1SCN9AMAPTMAOB | |
| SCHEMBL28294317 | 0.81 | SCN9A (0.45) | CCNCCDK8CDK19SCN9AMAOB | |
| SCHEMBL28292586 | 0.77 | SCN9A (0.44) | SCN9AMAOB | |
| SCHEMBL28940985 | 0.77 | SCN9A (0.44) | SCN9AMAOB | |
| SCHEMBL28284688 | 0.77 | CCNC (0.43) | CCNCCDK8CDK19MAPT | |
| SCHEMBL22341957 | 0.74 | CNR2 (0.48) | CNR2 | |
| SCHEMBL28292579 | 0.72 | CNR2 (0.50) | CNR2SCN9AMAOB | |
| SCHEMBL28940978 | 0.72 | SCN9A (0.39) | CNR2CCNCCDK8CDK19SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |