SCHEMBL28294338

SCHEMBL28294338

NOC(=O)[C@H](CCC(N)=O)N(C=O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
PKM P14618 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
LTA4H P09960 1/20 0.34
KMT2A Q03164 3/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
EPOR P19235 1/20 0.31
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KDM4E B2RXH2 2/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28292698 0.85 CHRNB2 (0.38) SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL28292748 0.81 SRR (0.43) CYP1A2PKMKMT2AALDH1A1GAA
SCHEMBL19975122 0.71 ALDH1A1 (0.40) SMN1; SMN2NPSR1CHRNB2CHRNB4CHRNA3
SCHEMBL28137455 0.70 KMT2A (0.42) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL28137456 0.70 KMT2A (0.42) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL27291807 0.69 ATM (0.38) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL28511256 0.69 MMP2 (0.37) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL5595913 0.69 KMT2A (0.41) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL5595916 0.69 KMT2A (0.41) SMN1; SMN2CYP1A2CYP2D6PKMNPSR1
SCHEMBL10791747 0.68 SMPD2 (0.40) SMN1; SMN2CYP1A2CYP2D6NPSR1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025574-B Thermal recording medium 三光株式会社 2019-04-16 CN disclosed