Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292973 | 0.74 | OPRD1 (0.43) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL28780266 | 0.70 | ALDH1A1 (0.47) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL27762347 | 0.70 | ALDH1A1 (0.47) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL4921546 | 0.69 | OPRD1 (1.00) | OPRD1OPRK1OPRM1CYP2D6CYP3A4 | |
| SCHEMBL4922061 | 0.68 | OPRD1 (1.00) | OPRD1OPRK1OPRM1 | |
| Efetozole SCHEMBL21698044 | 0.68 | BRD4 (0.51) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| Efetozole SCHEMBL2109012 | 0.68 | BRD4 (0.51) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL4914490 | 0.68 | OPRD1 (1.00) | OPRD1OPRK1OPRM1 | |
| SCHEMBL20508884 | 0.67 | MEN1 (0.45) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL20569604 | 0.67 | KDM4E (0.53) | OPRD1OPRK1OPRM1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776510-A | A kind of N- substituted imidazole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |