Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | USP19 | O94966 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508884 | 0.76 | MEN1 (0.45) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL3763386 | 0.76 | MEN1 (0.45) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL28294613 | 0.74 | OPRD1 (0.53) | OPRD1OPRK1OPRM1OPRL1BRD4 | |
| SCHEMBL28301285 | 0.73 | BRD4 (0.40) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL16136368 | 0.71 | FPR2 (0.48) | OPRD1OPRK1OPRM1BRD4ALDH1A1 | |
| SCHEMBL28780266 | 0.70 | ALDH1A1 (0.47) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL27762347 | 0.70 | ALDH1A1 (0.47) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL28957007 | 0.68 | OPRD1 (0.39) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| SCHEMBL16133639 | 0.68 | MAPT (0.46) | OPRD1OPRK1OPRM1BRD4MEN1 | |
| Efetozole SCHEMBL21698044 | 0.68 | BRD4 (0.51) | OPRD1OPRK1OPRM1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776510-A | A kind of N- substituted imidazole formate ester derivative and application thereof | 成都安诺晨创医药科技有限公司 | 2019-05-21 | — | — | CN | disclosed |