Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13176135 | 0.88 | TSHR (0.41) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL28243014 | 0.82 | — | — | |
| SCHEMBL28381521 | 0.82 | ALDH1A1 (0.44) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL148042 | 0.80 | ADRA2A (0.46) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6695792 | 0.80 | THRB (0.55) | TSHRCHRM5CHRM1CHRM3TDP1 | |
| SCHEMBL31463659 | 0.80 | THRB (0.36) | TSHRTDP1THRBEPHX1ALDH1A1 | |
| SCHEMBL31605721 | 0.78 | ADRA2A (0.45) | TSHRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7711519 | 0.77 | ALOX15 (0.44) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL17449668 | 0.77 | NAAA (0.45) | TSHRLMNACYP2C19TDP1THRB | |
| SCHEMBL18641404 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902007-B1 | DENTAL FILLING REPAIRING MATERIAL | TOKUYAMA DENTAL CORP (JP) | 2019-01-09 | — | — | EP | claimed |
| US-11618841-B2 | Sealant material | HENKEL AG & CO. KGAA (DE) | 2023-04-04 | — | — | US | disclosed |
| US-20190241781-A1 | SEALANT MATERIAL | Henkel IP & Holding GmbH (DE) | 2019-08-08 | — | — | US | disclosed |