Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122833 | 0.95 | ACHE (0.40) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL29262263 | 0.89 | TSHR (0.39) | ACHELMNATSHRCHRM2CHRM4 | |
| SCHEMBL10388828 | 0.85 | ACHE (0.41) | ACHETSHRALDH1A1THRB | |
| SCHEMBL9421249 | 0.84 | TSHR (0.55) | ACHETSHRALDH1A1THRB | |
| SCHEMBL24496157 | 0.81 | ALDH1A1 (0.41) | ACHETSHRALDH1A1THRB | |
| SCHEMBL16803336 | 0.80 | TSHR (0.50) | ACHETSHRTHRB | |
| SCHEMBL2612360 | 0.80 | ALDH1A1 (0.45) | ACHETSHRALDH1A1 | |
| SCHEMBL141759 | 0.79 | TSHR (0.55) | LMNATSHRALDH1A1 | |
| SCHEMBL5528349 | 0.79 | THRB (0.41) | ACHETSHRALDH1A1THRB | |
| SCHEMBL8949910 | 0.79 | THRB (0.41) | ACHETSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880021-A | Polymer and preparation method thereof, ROS response type siRNA nano-micelle and its application | 河南大学 | 2019-06-14 | — | — | CN | claimed |
| CN-109880021-B | Polymer and preparation method thereof, ROS response type siRNA nano micelle and application thereof | 河南大学 | 2020-03-27 | — | — | CN | disclosed |
| CN-109880021-A | Polymer and preparation method thereof, ROS response type siRNA nano-micelle and its application | 河南大学 | 2019-06-14 | — | — | CN | disclosed |