Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28296409 | 0.84 | ALDH1A1 (0.41) | CTSBCTSSCTSKALDH1A1MEN1 | |
| Ethoxycarbonyl Group SCHEMBL28957488 | 0.83 | GAA (0.42) | CTSBCTSSCTSKCSF1RCDK4 | |
| SCHEMBL28294734 | 0.81 | LMNA (0.41) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| Ethoxycarbonyl Group SCHEMBL28873297 | 0.80 | GAA (0.48) | OPRL1ALDH1A1MAPTHPGDHSD17B10 | |
| Ethoxycarbonyl Group SCHEMBL28294731 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL28744942 | 0.76 | L3MBTL1 (0.46) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL4005605 | 0.70 | NPY2R (0.62) | ALDH1A1MEN1MAPTHPGDKMT2A | |
| SCHEMBL20883645 | 0.67 | ALDH1A1 (0.47) | OPRL1ALDH1A1MAPTHTR6ROCK2 | |
| Hydrochloric Acid SCHEMBL30163875 | 0.66 | OPRL1 (0.42) | HRH4CTSLCTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL29232318 | 0.66 | OPRL1 (0.42) | HRH4CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |