Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | NPY2R | P49146 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296408 | 0.83 | LTA4H (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL28957487 | 0.81 | GAA (0.43) | LMNAGAAMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28294735 | 0.81 | HRH4 (0.38) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL28873296 | 0.78 | MAPT (0.50) | LMNAGAAALDH1A1MAPTHSD17B10 | |
| SCHEMBL28294730 | 0.77 | ALDH1A1 (0.53) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28744942 | 0.75 | L3MBTL1 (0.46) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL28294727 | 0.68 | NR3C1 (0.42) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL23444657 | 0.68 | XDH (0.46) | LMNAGAAMEN1KMT2AALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28296409 | 0.65 | ALDH1A1 (0.41) | GAAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6052407 | 0.65 | GAA (0.60) | LMNAGAAALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-A | A kind of N- benzyl-N- aryl sulfonic acid amides analog derivative and preparation and application | 杭州壹瑞医药科技有限公司 | 2019-04-19 | — | — | CN | disclosed |