Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.52 |
| ▸ | RXRB | P28702 | 3/20 | 0.52 |
| ▸ | RXRG | P48443 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12980377 | 0.91 | MAOB (0.55) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL12980350 | 0.89 | SMN1; SMN2 (0.62) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL12980387 | 0.85 | PTGER1 (0.54) | PTGER1MRGPRX4NPC1RAB9AKMT2A | |
| SCHEMBL2634130 | 0.83 | NR4A2 (0.63) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL9204010 | 0.82 | RXRA (0.48) | RXRARXRBRXRGNR4A2NR4A1 | |
| SCHEMBL12980479 | 0.81 | CFD (0.47) | SMN1; SMN2 | |
| SCHEMBL12980561 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2A | |
| SCHEMBL644658 | 0.79 | SMPD1 (0.48) | RXRARXRBRXRGMRGPRX4NPC1 | |
| SCHEMBL8409338 | 0.79 | PTGER1 (0.53) | RXRARXRBRXRGPTGER1MRGPRX4 | |
| SCHEMBL6779534 | 0.78 | MAOB (0.65) | RXRARXRBNR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045552-B | Medicinal compound as neuroprotective agent | 江苏先声药业有限公司 | 2019-06-11 | — | — | CN | disclosed |