Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25789837 | 0.78 | LMNA (0.48) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL28268206 | 0.78 | TSHR (0.50) | MAPTCA2ALDH1A1LMNAF2 | |
| SCHEMBL11310744 | 0.78 | ALDH1A1 (0.51) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL28049658 | 0.78 | MAPT (0.53) | MAPTCA2ALDH1A1KDM4EHPGD | |
| SCHEMBL10815691 | 0.77 | MAPT (0.50) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL17278786 | 0.77 | CA2 (0.50) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL29393881 | 0.77 | CA2 (0.54) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL3889326 | 0.77 | CA2 (0.54) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL28295688 | 0.76 | PGR (0.41) | MAPTCA2ALDH1A1KDM4ELMNA | |
| SCHEMBL15015034 | 0.73 | CA2 (0.50) | MAPTCA2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761875-A | A kind of new method constructing amido bond | 盐城工学院 | 2019-05-17 | — | — | CN | claimed |
| CN-109776526-A | Condensed cyclic triazole-(sulfonyl) Triazenes derivative and its preparation method and use | 西南医科大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109761875-A | A kind of new method constructing amido bond | 盐城工学院 | 2019-05-17 | — | — | CN | disclosed |