SCHEMBL28295524

SCHEMBL28295524

CCOC(=O)c1nc(-c2ccco2)oc1C

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 7/20 0.62
PDCD4 Q53EL6 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 6/20 0.51
PKM P14618 1/20 0.51
ADORA2B P29275 2/20 0.50
KMT2A Q03164 3/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 2/20 0.46
ALOX15 P16050 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 2/20 0.45
GAA P10253 2/20 0.45
ADORA3 P0DMS8 2/20 0.45
ADORA2A P29274 2/20 0.45
ADORA1 P30542 2/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295526 0.88 TARBP2 (0.65) TARBP2PDCD4L3MBTL1ALDH1A1PKM
SCHEMBL2485336 0.79 TARBP2 (0.94) TARBP2PDCD4ALDH1A1KMT2AHSD17B10
SCHEMBL27351138 0.77 ALDH1A1 (0.47) L3MBTL1ALDH1A1PKMKMT2AHSD17B10
SCHEMBL3436254 0.77 L3MBTL1 (0.58) L3MBTL1ALDH1A1PKMADORA2BKMT2A
SCHEMBL28295518 0.77 TARBP2 (1.00) TARBP2PDCD4ALDH1A1KMT2AHSD17B10
SCHEMBL4918154 0.76 TARBP2 (1.00) TARBP2PDCD4ALDH1A1PKMKMT2A
SCHEMBL7907774 0.75 TARBP2 (0.82) TARBP2PDCD4ALDH1A1KMT2AHSD17B10
SCHEMBL28295536 0.75 TARBP2 (0.77) TARBP2PDCD4ALDH1A1PKMKMT2A
SCHEMBL17768259 0.75 TARBP2 (0.82) TARBP2PDCD4ALDH1A1KMT2AHSD17B10
SCHEMBL11622240 0.75 TARBP2 (0.61) TARBP2PDCD4ALDH1A1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed