SCHEMBL28295526

SCHEMBL28295526

Cc1oc(-c2ccco2)nc1C(=O)OCCO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TARBP2 Q15633 6/20 0.65
PDCD4 Q53EL6 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 5/20 0.40
PKM P14618 2/20 0.40
ADORA2B P29275 1/20 0.40
HSD17B10 Q99714 3/20 0.39
MAPT P10636 3/20 0.39
ALOX15 P16050 2/20 0.39
TSHR P16473 2/20 0.39
GAA P10253 1/20 0.39
TDP2 O95551 1/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28295524 0.88 TARBP2 (0.62) TARBP2PDCD4L3MBTL1ALDH1A1PKM
SCHEMBL28297253 0.81 TARBP2 (0.95) TARBP2PDCD4L3MBTL1ALDH1A1HSD17B10
SCHEMBL28297254 0.79 TARBP2 (1.00) TARBP2PDCD4L3MBTL1ALDH1A1HSD17B10
SCHEMBL28297243 0.78 TARBP2 (0.81) TARBP2PDCD4ALDH1A1PKMHSD17B10
SCHEMBL28297247 0.77 TARBP2 (0.67) TARBP2PDCD4ALDH1A1PKMHSD17B10
SCHEMBL28297236 0.76 TARBP2 (0.69) TARBP2PDCD4ALDH1A1MAPTHPGD
SCHEMBL28297234 0.76 TARBP2 (0.65) TARBP2PDCD4ALDH1A1MAPTTDP2
SCHEMBL27351138 0.74 ALDH1A1 (0.47) L3MBTL1ALDH1A1PKMHSD17B10MAPT
SCHEMBL28295706 0.73 TARBP2 (0.66) TARBP2PDCD4L3MBTL1ALDH1A1HSD17B10
SCHEMBL8688232 0.72 DRD2 (0.46) L3MBTL1ALDH1A1PKMHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810071-A A kind of miRNA biosynthesis inhibitor 中国科学院成都生物研究所 2019-05-28 CN disclosed