SCHEMBL28295619

SCHEMBL28295619

CC(=O)O[SiH](OC(C)=O)c1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.44
HNF4A P41235 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
BCAT2 O15382 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MAPT P10636 1/20 0.37
POLB P06746 2/20 0.37
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXRA P19793 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204167 0.72 ALDH1A1 (0.42) BACE1SMN1; SMN2HSP90AA1MAPTPOLB
Biphenyl SCHEMBL19897501 0.72 SMN1; SMN2 (0.50) BACE1SMN1; SMN2MAPTPDCD1CD274
Acetic Acid SCHEMBL27275667 0.71 BCAT2 (0.54) BACE1HNF4ASMN1; SMN2MEN1KMT2A
Biphenyl SCHEMBL28295622 0.71 SMN1; SMN2 (0.48) BACE1SMN1; SMN2MAPTPDCD1CD274
SCHEMBL11530828 0.69 SMN1; SMN2 (0.50) BACE1HNF4ASMN1; SMN2MEN1KMT2A
Acetic Acid SCHEMBL31401913 0.69 HNF4A (0.53) BACE1HNF4ASMN1; SMN2MEN1KMT2A
SCHEMBL27849556 0.68 ADORA3 (0.55) BACE1SMN1; SMN2ADORA3ADORA2AADORA1
SCHEMBL28650304 0.68 BACE1 (0.47) BACE1HNF4ASMN1; SMN2MEN1KMT2A
SCHEMBL3728321 0.68 KDM4E (0.58) BACE1SMN1; SMN2MEN1KMT2AADORA3
Bicarbonate SCHEMBL9330276 0.67 KDM4E (0.56) BACE1SMN1; SMN2MEN1KMT2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109716544-A LED Encapulant composition 日产化学株式会社 2019-05-03 CN disclosed