Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 3/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792980 | 0.82 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2ALDH1A1P2RX1P2RX3 | |
| SCHEMBL28486552 | 0.80 | PRKCG (0.37) | LMNASMN1; SMN2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL8495236 | 0.78 | ALDH1A1 (0.42) | LMNASMN1; SMN2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL3253414 | 0.73 | MEN1 (0.42) | LMNASMN1; SMN2ALDH1A1P2RX1P2RX3 | |
| SCHEMBL10613637 | 0.72 | PTGS1 (0.53) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL22214489 | 0.71 | GBA1 (0.51) | ALDH1A1GBA1KDM4E | |
| SCHEMBL5323524 | 0.70 | CES1 (0.53) | ALDH1A1ALDH2ALDH3A1CDC25ACES1 | |
| SCHEMBL32677342 | 0.70 | NR1H2 (0.38) | LMNASMN1; SMN2ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL20616460 | 0.69 | CHEK1 (0.32) | PRKCQ | |
| SCHEMBL459465 | 0.68 | PRKCD (0.45) | LMNAALDH1A1ALDH2ALDH3A1GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824585-A | A kind of method that presence of acidic ionic liquid catalyst prepares 1- aryl -2- quinolyl alcohol cpd | 马鞍山市泰博化工科技有限公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109824585-A | A kind of method that presence of acidic ionic liquid catalyst prepares 1- aryl -2- quinolyl alcohol cpd | 马鞍山市泰博化工科技有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-109824585-A | A kind of method that presence of acidic ionic liquid catalyst prepares 1- aryl -2- quinolyl alcohol cpd | 马鞍山市泰博化工科技有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-109824585-A | A kind of method that presence of acidic ionic liquid catalyst prepares 1- aryl -2- quinolyl alcohol cpd | 马鞍山市泰博化工科技有限公司 | 2019-05-31 | — | — | CN | disclosed |