Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 5/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295668 | 0.80 | LMNA (0.41) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL8495236 | 0.74 | ALDH1A1 (0.42) | P2RX4P2RX1P2RX3LMNAKDM4E | |
| SCHEMBL10613637 | 0.68 | PTGS1 (0.53) | ALDH1A1ALDH2ALDH3A1KMT2ACES1 | |
| SCHEMBL5323524 | 0.66 | CES1 (0.53) | ALDH1A1ALDH2ALDH3A1KMT2ACES1 | |
| SCHEMBL32677342 | 0.66 | NR1H2 (0.38) | PRKCDLMNAKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL11792980 | 0.65 | SMN1; SMN2 (0.46) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL459465 | 0.64 | PRKCD (0.45) | PRKCGPRKCBPRKCAPRKCHPRKCE | |
| SCHEMBL29094467 | 0.64 | MEN1 (0.43) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL4595897 | 0.63 | KMT2A (0.47) | P2RX4P2RX1P2RX3P2RX7LMNA | |
| SCHEMBL28537893 | 0.63 | CES1 (0.45) | PRKCGPRKCBPRKCAPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824585-B | Method for preparing 1-aryl-2-quinolyl ethanol compound under catalysis of acidic ionic liquid | 马鞍山市泰博化工科技有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-109824585-B | Method for preparing 1-aryl-2-quinolyl ethanol compound under catalysis of acidic ionic liquid | 马鞍山市泰博化工科技有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-109824585-B | Method for preparing 1-aryl-2-quinolyl ethanol compound under catalysis of acidic ionic liquid | 马鞍山市泰博化工科技有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-109824585-B | Method for preparing 1-aryl-2-quinolyl ethanol compound under catalysis of acidic ionic liquid | 马鞍山市泰博化工科技有限公司 | 2020-08-14 | — | — | CN | disclosed |