SCHEMBL28295875

SCHEMBL28295875

FC(F)=C(F)c1cc(F)c(C(F)=C(F)F)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.33
CES1 P23141 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7882123 0.79 CES2 (0.33) CES2CES1
SCHEMBL7765933 0.77 DGAT1 (0.33)
SCHEMBL13971043 0.76
SCHEMBL28294995 0.72 CA1 (0.39) CES2CES1
SCHEMBL8727687 0.72
SCHEMBL20032413 0.69 CES2 (0.40) CES2CES1
SCHEMBL21218738 0.69
SCHEMBL7639747 0.68
SCHEMBL2672944 0.67 BACE1 (0.39)
SCHEMBL15433390 0.65 CES2 (0.36) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790091-A Replace bis- (trifluoro vinyl) benzene compounds 东曹精细化工株式会社 2019-05-21 CN claimed
CN-109790091-A Replace bis- (trifluoro vinyl) benzene compounds 东曹精细化工株式会社 2019-05-21 CN disclosed