SCHEMBL28295993

SCHEMBL28295993

CN(C)C(CCO)c1ccccc1.c1c[nH]nn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.45
CHRNB4 P30926 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA4 P43681 1/20 0.45
CHRM2 P08172 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SCN1A P35498 2/20 0.38
SCN2A Q99250 2/20 0.38
SCN3A Q9NY46 2/20 0.38
GAA P10253 1/20 0.36
TRPA1 O75762 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 2/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
OPRM1 P35372 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28144244 0.82 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL28144242 0.82 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL9995387 0.82 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL5398515 0.82 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL12071516 0.82 CHRNB2 (0.56) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL27721341 0.81 TRPA1 (0.49) TRPA1ALDH1A1
Hydrochloric Acid SCHEMBL17710458 0.80 CHRNB2 (0.54) CHRNB2CHRNB4CHRNA3CHRNA4SLC6A2
Bromide SCHEMBL28176004 0.80 CHRNB2 (0.54) CHRNB2CHRNB4CHRNA3CHRNA4CHRM2
SCHEMBL27659215 0.80 RIPK1 (0.40) TRPA1KDM4ELMNATSHRCYP2D6
SCHEMBL28854326 0.76 SIGMAR1 (0.35) CHRM2SLC6A2SLC6A4SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694770-A One Albatra metal cutting fluid composite and preparation method thereof 上海樱花化研化工科技有限公司 2019-04-30 CN disclosed