SCHEMBL28296080

SCHEMBL28296080

O=C1C=C(c2ccccc2)C(=O)O1.[CH3]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 4/20 0.48
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
PTPN1 P18031 2/20 0.42
PTPRC P08575 1/20 0.42
PTPRF P10586 1/20 0.42
CDC25B P30305 1/20 0.42
HSD17B3 P37058 1/20 0.42
MAPT P10636 4/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 1/20 0.39
MEN1 O00255 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 5/20 0.36
ALOX12 P18054 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GAA P10253 2/20 0.36
HPGD P15428 2/20 0.36
CCR6 P51684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28277789 0.98 BACE1 (0.50) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL210321 0.98 BACE1 (0.50) BACE1MAOAMAOBPTPN1PTPRC
Benzene SCHEMBL28133344 0.98 BACE1 (0.50) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL9467973 0.93 HSD17B3 (0.50) BACE1MAOAMAOBPTPN1PTPRC
Naphthalene SCHEMBL28134279 0.91 BACE1 (0.45) BACE1MAOAMAOBPTPN1PTPRC
Diphenylether SCHEMBL28133345 0.86 LTA4H (0.46) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL11726616 0.86 BACE1 (0.41) BACE1MAOAMAOBPTPN1PTPRC
Maleic Anhydride SCHEMBL10998831 0.84 MAOA (0.41) BACE1MAOAMAOBPTPN1PTPRC
SCHEMBL29242287 0.83 KMO (0.42) BACE1MAOAHSD17B3MAPTLMNA
SCHEMBL9803793 0.80 BACE1 (0.43) BACE1MAOAMAOBPTPN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715768-A Lubricant oil composite comprising biodiesel fuel and dispersing agent 雪佛龙奥伦耐技术有限责任公司 2019-05-03 CN disclosed