Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210321 | 0.95 | BACE1 (0.50) | HSD17B3PTPN1BACE1CTRCMAOA | |
| Benzene SCHEMBL28277789 | 0.95 | BACE1 (0.50) | HSD17B3PTPN1BACE1CTRCMAOA | |
| Benzene SCHEMBL28133344 | 0.95 | BACE1 (0.50) | HSD17B3PTPN1BACE1CTRCMAOA | |
| SCHEMBL28296080 | 0.93 | BACE1 (0.48) | HSD17B3PTPN1BACE1CTRCMAOA | |
| Naphthalene SCHEMBL28134279 | 0.89 | BACE1 (0.45) | HSD17B3PTPN1BACE1MAOAMAOB | |
| SCHEMBL29242287 | 0.85 | KMO (0.42) | HSD17B3BACE1MAOAALDH1A1PGR | |
| Diphenylether SCHEMBL28133345 | 0.84 | LTA4H (0.46) | HSD17B3PTPN1BACE1MAOAMAOB | |
| SCHEMBL11726616 | 0.84 | BACE1 (0.41) | HSD17B3PTPN1BACE1MAOAMAOB | |
| SCHEMBL27523252 | 0.82 | ALDH1A1 (0.41) | HSD17B3PTPN1BACE1MAOAMAOB | |
| Maleic Anhydride SCHEMBL10998831 | 0.82 | MAOA (0.41) | HSD17B3PTPN1BACE1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105542134-A | Lactic acid-based aliphatic-aromatic random copolymer | CHANGCHUN INST APPLIED CHEMISTRY CAS | 2016-05-04 | — | — | CN | disclosed |
| CN-105440267-A | Aliphatic-aromatic-polylactic acid random copolymer and preparation method thereof | CHANGCHUN INST APPLIED CHEMISTRY CAS | 2016-03-30 | — | — | CN | disclosed |
| CN-105367771-A | Lactyl aliphatic random copolymer and preparation method thereof | CHANGCHUN INST APPLIED CHEMISTRY CAS | 2016-03-02 | — | — | CN | disclosed |
| US-5206392-A | Reacting arylacetonitriles with glyoxylic acid in presence of base, hydrolyzing, cyclizing | AMERICAN CYANAMID COMPANY (US) | 1993-04-27 | — | — | US | disclosed |