Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19815338 | 0.79 | BCAT2 (0.55) | ALDH1A1ATMBRD4MAP2K2MAP2K1 | |
| SCHEMBL28296106 | 0.78 | PRKAB2 (0.45) | ALDH1A1ATMBRD4MAP2K2MAP2K1 | |
| SCHEMBL26240985 | 0.78 | MAP2K2 (0.42) | ALDH1A1ATMBRD4MAP2K2MAP2K1 | |
| SCHEMBL1788703 | 0.76 | BCAT2 (0.59) | ALDH1A1BRD4MYCBCAT2IKBKB | |
| SCHEMBL7890739 | 0.74 | ALDH1A1 (0.46) | ALDH1A1BRD4JAK2MAP2MYC | |
| SCHEMBL28294213 | 0.73 | MAP2K2 (0.48) | ALDH1A1BRD4MAP2K2MAP2K1MYC | |
| SCHEMBL5742619 | 0.71 | MYC (0.53) | ALDH1A1BRD4MAP2MYCBCAT2 | |
| SCHEMBL3135445 | 0.71 | MYC (0.53) | ALDH1A1BRD4MYCBCAT2IKBKB | |
| SCHEMBL7577374 | 0.71 | BCAT2 (0.45) | BRD4MYCBCAT2IKBKBSLC9A1 | |
| SCHEMBL3701689 | 0.70 | MYC (0.51) | ALDH1A1BRD4JAK2MAP2K2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-A | Medical compounds | 阿尔麦克探索有限公司 | 2019-05-21 | — | — | CN | disclosed |