Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 7/20 | 0.42 |
| ▸ | HTR2B | P41595 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059728 | 0.78 | MAPT (0.50) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28776450 | 0.76 | TOP2A (0.50) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL29724074 | 0.76 | TOP2A (0.50) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL28296390 | 0.76 | HRH4 (0.38) | LMNAHTR2CHTR2BCYP2C9HTR2A | |
| SCHEMBL7236252 | 0.71 | TOP2A (0.43) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6582872 | 0.69 | ALDH1A1 (0.56) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL16229892 | 0.67 | NOS1 (0.53) | HTR2CHTR2BNOS1CYP2C19HTR2A | |
| SCHEMBL9668536 | 0.66 | ALDH1A1 (0.47) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL16329562 | 0.66 | TOP2A (0.55) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL21833459 | 0.66 | LMNA (0.51) | MAPTLMNAGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776411-A | Mustargen Carbostyril derivative and its preparation method and application | 石家庄学院 | 2019-05-21 | — | — | CN | disclosed |