Pimagedine

Pimagedine

SCHEMBL28296498

N.N=C(N)NN.NC(N)=NO

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PTGS2 P35354 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pimagedine SCHEMBL28321364 0.83
Pimagedine SCHEMBL27366958 0.79 ALDH1A1 (0.43) NOS1ALDH1A1PTGS2HSD17B10CYP1A2
Pimagedine SCHEMBL15307 0.79
Pimagedine SCHEMBL7763659 0.79 ALDH1A1 (0.43) NOS1ALDH1A1PTGS2HSD17B10CYP1A2
Pimagedine SCHEMBL28296497 0.79 NOS1 (0.41) NOS1
Pimagedine SCHEMBL686876 0.78
Pimagedine SCHEMBL23779762 0.75
Pimagedine SCHEMBL3818920 0.75
Pimagedine SCHEMBL19122 0.75
Pimagedine SCHEMBL10340639 0.75 ALDH1A1 (0.40) NOS1ALDH1A1PTGS2HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689027-A Triglycerides aural preparations and application thereof 奥德纳米有限公司 2019-04-26 CN disclosed