Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695792 | 0.78 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL27803225 | 0.77 | RAB9A (0.37) | KDM4EALDH1A1RAB9AL3MBTL1HSD11B1 | |
| SCHEMBL27202095 | 0.71 | LRRK2 (0.37) | KDM4E | |
| SCHEMBL31686263 | 0.71 | TDP1 (0.37) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL10833748 | 0.70 | MAPK1 (0.41) | KDM4E | |
| SCHEMBL27964274 | 0.68 | L3MBTL1 (0.34) | L3MBTL1 | |
| SCHEMBL25215103 | 0.64 | CA12 (0.36) | — | |
| SCHEMBL29034380 | 0.64 | MYC (0.35) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL25219822 | 0.64 | CA2 (0.38) | KDM4EALDH1A1 | |
| SCHEMBL29077065 | 0.63 | COMT (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | disclosed |