Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953506 | 0.75 | PARP1 (0.50) | TDP1LMNAKDM4EL3MBTL1PARP1 | |
| SCHEMBL28322999 | 0.73 | NNMT (0.46) | TDP1SIRT3CASP1CDC7KDM4E | |
| SCHEMBL27202095 | 0.71 | LRRK2 (0.37) | LMNAKDM4ELRRK2MEN1KMT2A | |
| SCHEMBL164572 | 0.71 | SIRT3 (0.38) | TDP1SIRT3CASP1CDC7KDM4E | |
| SCHEMBL10877795 | 0.71 | KDM4E (0.41) | TDP1SIRT3CASP1CDC7KDM4E | |
| SCHEMBL28309038 | 0.71 | SIRT3 (0.38) | TDP1SIRT3CASP1KDM4EL3MBTL1 | |
| SCHEMBL28296833 | 0.71 | KDM4E (0.32) | KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL10695792 | 0.71 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL31092388 | 0.69 | CASP1 (0.49) | TDP1SIRT3CASP1KDM4EL3MBTL1 | |
| SCHEMBL31092393 | 0.69 | CASP1 (0.40) | TDP1SIRT3CASP1CDC7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595244-B2 | Small molecule inhibitors of mammalian SLC6A19 function | JNANA THERAPEUTICS INC. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20250289797-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. | 2025-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289797-A1 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | SLC18A2, SLC6A19, SLC1A1 | TDP1 1116/4885SIRT3 3687/4885CASP1 4866/4885 |
| US-12595244-B2 | Small molecule inhibitors of mammalian SLC6A19 function | SLC6A19, SLC6A15, SLC19A1 | TDP1 1306/4885SIRT3 3570/4885CASP1 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.