Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28185107 | 0.76 | TSHR (0.47) | L3MBTL1CTRCPTPN1PTPN2PTPN6 | |
| SCHEMBL1462173 | 0.72 | TSHR (0.58) | ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL27451969 | 0.71 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1 | |
| SCHEMBL27825242 | 0.71 | CYP3A4 (0.48) | PTPN1PTPN2PTPN6 | |
| SCHEMBL28811060 | 0.69 | TSHR (0.46) | L3MBTL1ALDH1A1MTNR1AMTNR1BCLCN2 | |
| SCHEMBL28746195 | 0.69 | ALDH1A1 (0.53) | HSP90AA1L3MBTL1ALDH1A1 | |
| SCHEMBL27762362 | 0.67 | HNF4A (0.51) | PTPN1PTPN2PTPN6 | |
| SCHEMBL10506173 | 0.67 | SMN1; SMN2 (0.52) | ALDH1A1 | |
| SCHEMBL13070301 | 0.66 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PTPN1PTPN2PTPN6 | |
| SCHEMBL8892557 | 0.66 | PTPN1 (0.41) | PTPN1PTPN2PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824677-A | The preparation method for treating ovarian cancer Rui Kapabu | 江苏开元药业有限公司 | 2019-05-31 | — | — | CN | disclosed |