Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.43 |
| ▸ | CA1 | P00915 | 11/20 | 0.43 |
| ▸ | CA9 | Q16790 | 10/20 | 0.43 |
| ▸ | CA12 | O43570 | 9/20 | 0.43 |
| ▸ | CA7 | P43166 | 8/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323422 | 0.83 | CA2 (0.52) | CA2CA1CA9CA12CA7 | |
| SCHEMBL6841898 | 0.80 | CHRNA7 (0.59) | CA2CA1CA9CA12CA7 | |
| SCHEMBL22816321 | 0.79 | KDM4E (0.41) | CA2CA1CA9CA12CA7 | |
| SCHEMBL28297024 | 0.79 | ESR2 (0.53) | CA2CA1CA9CA12CA7 | |
| SCHEMBL14341830 | 0.78 | LMNA (0.59) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9494422 | 0.77 | LMNA (0.57) | CA2CA1CA9CA12CA7 | |
| SCHEMBL25039518 | 0.76 | ESR2 (0.48) | ESR2MEN1KMT2A | |
| SCHEMBL22048254 | 0.75 | ESR2 (0.56) | CA2CA1CA9CA12CA7 | |
| SCHEMBL22816328 | 0.75 | ESR2 (0.55) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9827832 | 0.75 | SLC18A3 (0.52) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715629-A | AZA-INDAZOLE COMPOUNDS FOR USE IN TENDON AND/OR LIGAMENT INJURIES | 诺华股份有限公司 | 2019-05-03 | — | — | CN | disclosed |