Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 9/20 | 0.55 |
| ▸ | CA1 | P00915 | 8/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341830 | 0.98 | LMNA (0.59) | CHRNA7LMNAHTTPTGES2CA2 | |
| SCHEMBL9494422 | 0.96 | LMNA (0.57) | CHRNA7LMNAHTTPTGES2CA2 | |
| SCHEMBL8323422 | 0.91 | CA2 (0.52) | CHRNA7HTTPTGES2CA2CA1 | |
| SCHEMBL10180298 | 0.83 | LMNA (0.65) | CHRNA7LMNAHTTPTGES2SMN1; SMN2 | |
| SCHEMBL28297024 | 0.82 | ESR2 (0.53) | CHRNA7PTGES2CA2CA1CA9 | |
| SCHEMBL22048254 | 0.82 | ESR2 (0.56) | CHRNA7PTGES2CA2CA1CA9 | |
| SCHEMBL22816328 | 0.82 | ESR2 (0.55) | CHRNA7PTGES2CA2CA1CA9 | |
| SCHEMBL9827832 | 0.82 | SLC18A3 (0.52) | CHRNA7LMNACA2CA1CA9 | |
| SCHEMBL10182181 | 0.81 | LMNA (0.68) | CHRNA7LMNAHTTPTGES2SMN1; SMN2 | |
| SCHEMBL28298642 | 0.81 | CHRNA7 (0.49) | CHRNA7CA2CA1CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106663-A1 | Inhibitors of fungal invasion | MICROBIA, INC. | 2004-06-03 | — | — | US | disclosed |
| EP-0510526-B1 | Use of sulfonamides as drug and new sulfonamides | HOFFMANN LA ROCHE (CH) | 1996-12-04 | — | — | EP | disclosed |
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0510526-A1 | Use of sulfonamides as drug and new sulfonamides | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106663-A1 | Inhibitors of fungal invasion | ERG28, MIF, MMP17 | CHRNA7 4749/4885LMNA 4392/4885HTT 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.