Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298624 | 0.86 | KIF11 (0.56) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL29993384 | 0.81 | PARP1 (0.73) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL6008297 | 0.81 | PARP1 (0.73) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL29540314 | 0.78 | GABRA1 (0.70) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL155013 | 0.78 | GABRA1 (0.70) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL6008321 | 0.77 | CTSV (0.69) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL31544362 | 0.77 | AHR (0.53) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL4136730 | 0.74 | KIF11 (0.89) | PARP1KIF11GABRA1GABRG2GABRB3 | |
| SCHEMBL3065870 | 0.74 | HPGD (0.43) | CA12CA9MEN1MAPTKMT2A | |
| SCHEMBL30272743 | 0.73 | CTSV (0.79) | PARP1KIF11GABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |