Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 5/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297101 | 0.86 | PARP1 (0.56) | KIF11PARP1CDK1CDK2CA9 | |
| SCHEMBL6008297 | 0.81 | PARP1 (0.73) | KIF11PARP1CA9CA12MAPT | |
| SCHEMBL29993384 | 0.81 | PARP1 (0.73) | KIF11PARP1CA9CA12MAPT | |
| SCHEMBL155013 | 0.78 | GABRA1 (0.70) | KIF11PARP1CA9CA12MAPT | |
| SCHEMBL29540314 | 0.78 | GABRA1 (0.70) | KIF11PARP1CA9CA12MAPT | |
| SCHEMBL6008321 | 0.77 | CTSV (0.69) | KIF11PARP1CDK1CDK2CA9 | |
| SCHEMBL28190463 | 0.77 | BRAF (0.65) | KIF11BRAFCA2CA5ACA9 | |
| Hydrochloric Acid SCHEMBL28326297 | 0.75 | BRAF (0.63) | KIF11BRAFCA2CA5ACA9 | |
| SCHEMBL4136730 | 0.74 | KIF11 (0.89) | KIF11PARP1GABRA1GABRG2GABRB3 | |
| SCHEMBL30272742 | 0.73 | CTSV (0.79) | KIF11PARP1CDK2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851550-A | 7- aminocarbazole sulfamide derivative and its preparation method and application | 中国医学科学院医药生物技术研究所 | 2019-06-07 | — | — | CN | disclosed |