Nitrogen

Nitrogen

SCHEMBL28297413

N#N.O=C1C(=O)N(Cc2ccccc2)c2cc(Br)ccc21

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.74
ALDH3A1 P30838 6/20 0.74
ALDH2 P05091 4/20 0.74
CHRM5 P08912 3/20 0.65
CHRM1 P11229 2/20 0.65
CHRM3 P20309 1/20 0.65
CES1 P23141 4/20 0.63
ACHE P22303 4/20 0.61
CASP3 P42574 2/20 0.53
BCHE P06276 2/20 0.51
CES2 O00748 1/20 0.51
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51
APAF1 O14727 2/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15206958 0.97 ALDH1A1 (0.78) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL5659265 0.85 ALDH1A1 (1.00) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL28026703 0.84 ACHE (0.67) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
Nitrogen SCHEMBL28298896 0.82 ALDH1A1 (0.93) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL29648466 0.81 ALDH1A1 (0.78) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
Nitrogen SCHEMBL27935052 0.80 ALDH1A1 (0.90) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL28370799 0.80 ALDH1A1 (0.58) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL4782178 0.80 CHRM5 (0.68) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL15215034 0.79 ALDH1A1 (0.67) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1
SCHEMBL27866584 0.79 ALDH1A1 (0.67) ALDH1A1ALDH3A1ALDH2CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109776384-A The double quaternary carbon dual oxide benzazolyl compounds of 3- aryl -3 '-amino and its synthetic method and application 华东师范大学 2019-05-21 CN disclosed