Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792243 | 0.91 | POLB (0.43) | ALDH1A1MAPK1NR1I2POLBLMNA | |
| Cadaverine Tartrate SCHEMBL27762982 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPK1NR1I2POLBSMN1; SMN2 | |
| SCHEMBL29067561 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2LMNATP53 | |
| SCHEMBL28156316 | 0.76 | TSHR (0.53) | ALDH1A1SMN1; SMN2LMNATP53L3MBTL1 | |
| SCHEMBL28332035 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1POLBSMN1; SMN2GAAMAPT | |
| SCHEMBL2728438 | 0.74 | ALDH1A1 (0.47) | ALDH1A1POLBSMN1; SMN2LMNATP53 | |
| SCHEMBL8627738 | 0.73 | POLB (0.46) | ALDH1A1MAPK1NR1I2POLBLMNA | |
| SCHEMBL7437555 | 0.73 | MTNR1A (0.49) | ALDH1A1MAPK1NR1I2POLBLMNA | |
| SCHEMBL7365805 | 0.73 | NR1H2 (0.47) | ALDH1A1MAPK1NR1I2SMN1; SMN2KCNA5 | |
| SCHEMBL3841166 | 0.72 | TDP1 (0.44) | ALDH1A1MAPK1NR1I2POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109867684-A | A kind of preparation method of II type bisulfate clopidogrel | 武汉武药制药有限公司 | 2019-06-11 | — | — | CN | disclosed |