Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28297788 | 0.91 | ALDH1A1 (0.38) | POLBALDH1A1MAPK1NR1I2TSHR | |
| SCHEMBL29067561 | 0.85 | ALDH1A1 (0.42) | POLBALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL28332035 | 0.82 | SMN1; SMN2 (0.54) | POLBALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL7437555 | 0.81 | MTNR1A (0.49) | POLBALDH1A1MAPK1NR1I2TSHR | |
| SCHEMBL8627738 | 0.81 | POLB (0.46) | POLBALDH1A1MAPK1NR1I2TSHR | |
| SCHEMBL28156316 | 0.81 | TSHR (0.53) | ALDH1A1TSHRHTTKMT2ALMNA | |
| SCHEMBL2435487 | 0.79 | ALDH1A1 (0.47) | POLBALDH1A1MAPK1NR1I2TSHR | |
| SCHEMBL5345206 | 0.79 | POLB (0.44) | POLBALDH1A1MAPK1NR1I2TSHR | |
| SCHEMBL29172367 | 0.79 | ALDH1A1 (0.38) | POLBALDH1A1TSHRRAB9ANPC1 | |
| SCHEMBL29873818 | 0.79 | ALDH1A1 (0.46) | POLBALDH1A1MAPK1NR1I2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3634978-A1 | TAU AGGREGATION INHIBITORS | Adrx, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| WO-2018226992-A1 | TAU AGGREGATION INHIBITORS | ADRX, INC. (US) | 2018-12-13 | — | — | WO | disclosed |
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | PROCTER & GAMBLE (US) | 2018-11-01 | — | — | US | disclosed |
| EP-3365324-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | The Procter and Gamble Company (US) | 2018-08-29 | — | — | EP | disclosed |
| CN-108349879-A | Synthesis of cyclohexanecarboxamide derivatives useful as sensates in consumer products | 宝洁公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
| WO-2006003671-A1 | A PROCESS FOR RESOLUTION OF METHYLAMINO(2-CHLOROPHENYL)ACETATE | BATTULA SRINIVASA REDDY (IN) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180312463-A1 | Synthesis of Cyclohexane Carboxamide Derivatives Useful as Sensates in Consumer Products | SRM, ACMSD, CUTA | POLB 2987/4885ALDH1A1 1211/4885MAPK1 3999/4885 |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, ACMSD, SRM | POLB 3398/4885ALDH1A1 922/4885MAPK1 3607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.